No. 2 - Akkha (Path of Het)
Of the Tombs of Amascut sub-bosses, Akkha is easily the most punishing, and he is the most likely boss to force you into a situation where you find yourself being punished.
Akkha tests your reflexes with the constant prayer switches and gear switches you will need to utilize, as he switches his combat style and also prays against two of the three combat styles at any given time.
You will need to destroy the four shadows that spawn around the arena each time you deplete Akkha’s life points by another 20%, and you will then need to lure Akkha to that quadrant to damage him.
Additionally, be sure to avoid the trailing orbs, and be prepared to memorize the markers on the floor when they light up to be able to stand on the proper section and thus avoid being hit with the blast attack.
Once his health is depleted, he restores 20% of it during the enrage phase, when he must be attacked with Melee. There will be orbs all over the arena that you need to avoid, made more challenging by the fact that he is able to switch quadrants if not killed in time.